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魏老師-生技特化品與生質燃料等研究


Dr. Yu-Hong Wei is a full professor/chairman of Biotechnology and Bioengineering in Yuan Ze University, Taiwan. His contributions to the academia and bio-industry are numerous, including the fermentation processes development on bio-specialty chemicals (such as surfactin), biocosmeticts (ectoine, ellagic acid, arbutin, pitera, etc.), biopharmaceuticals (prodigiosin, antibiotics), biopolymers (PHA) and biofuels (bioethanol), and environmental engineering. He has authored more than 70 SCI papers and book chapters and earned many awards and honors, including the Young Asian Biotechnologist Prize 2010 by the Society for Biotechnology, Japan (SBJ) and the highest research performance award in Yuan Ze University. The main contribution Prof. Wei made is in the application of molecular biology methods and biochemical engineering techniques to the production of many novel compounds. Some of these products are now developed by local industrial partners. He is also active in academia-industry collaboration and service works in Taiwan’s science


魏毓宏 博士目前是台灣元智大學生物科技與工程研究所 教授兼所長,研究專長涵蓋:生技特化品、生技化妝品、生技醫藥品、生物高分子材料、生質燃料及環境工程等領域。魏毓宏教授 發表SCI期刊學術論文已超過70餘篇,學術成果豐碩。學術榮譽包含榮獲2010日本生技學會頒發之生技專家國際獎、有庠傑出教授獎、元智大學研究傑出獎等。


A. Journal papers (SCI) (Impact Factor2013ISI資料庫為準

1. Wei-Chuan, Ruey-Shin Juang and Yu-Hong Wei* (2015) Applications of a lipopeptidebiosurfactant, surfactin, produced bymicroorganisms.,Biochem. Eng. J., 103, 158-169, SCI. (Impact Factor: 2.467, Ranking: 32/134, subject categories: Engineering, Chemical, published: August, 2015).

2. Yuan-Ming Hsu, Chun-Hsing Liao, Yu-Hong Wei, Hsu-Wei Fang, Hsiang-Huan Hou, Chia-Chun Chen, Chih-Hung Chang* (2014) Daptomycin-Loaded Polymethylmethacrylate Bone Cementfor Joint Arthroplasty Surgery., Artif. Organs, 38, 484-492, SCI. (Impact Factor: 1.870, Ranking: 30/76, subject categories: Engineering, Biomedical, published: June, 2014).

3. Bo-Yann Chen, Tz-Jau Shiau, Jhao-Yin Hung, Yu-Hong Wei* and Chi-Wei (John) Lan (2014) Feasibility study on production of biodegradable polymer and wastewater treatment using Aeromonas strains for materials recycling. J. Taiwan Inst. Chem. Eng., 43, 455-458, SCI. (Impact Factor: 2.637, Ranking: 23/133, subject categories: Engineering, Chemical, published: March, 2014).

4. Yu-Tze. Horng, Chih-Ching Chien, C.-T. Huang, Yu-Hong Wei*, Shan-Yu Chen, John Chi-Wei Lan, Po-Chi Soo (2013) Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with co-expressed propionate permease (prpP), beta-ketothiolase B (bktB), and propionate-CoA synthase (prpE) in Escherichia coli., Biochem. Eng. J., 78, 73-79, SCI. (Impact Factor: 2.467, Ranking: 32/134, subject categories: Engineering, Chemical, published: September, 2013).

5. Bor-Yann Chen, Jhao-Yin Hung, Tz-Jau Shiau, Yu-Hong Wei* (2013) Exploring two-stage fermentation strategy of polyhydroxyalkanoate production using Aeromonas hydrophila., Biochem. Eng. J., 78, 80-84, SCI. (Impact Factor: 2.467, Ranking: 32/134, subject categories: Engineering, Chemical, published: September, 2013).

6. Wei-Chuan Chen, Wan-Ju Yu, Chia-Che Chang, Jo-Shu Chang, Shih-Horng Huang, Chih-Hung Chang, Shan-Yu Chen, Chih-Ching Chien, Chao-Ling Yao, Wen-Ming Chen, Yu-Hong Wei* (2013) Enhancing production of prodigiosin from Serratia marcescens C3 by statistical experimental design and porous carrier addition strategy., Biochem. Eng. J., 78, 93-100, SCI. (Impact Factor: 2.467, Ranking: 32/134, subject categories: Engineering, Chemical, published: September, 2013).

7. Wei-Chuan Chen, Yu-Hong Wei, I-Ming Chu, and Chao-Ling Yao* (2013) Effect of chondroitin sulfate C on the in vitro and in vivo chondrogenesis of mesenshymal stem cells in crosslinked type II collagen scaffolds., J. Tissue Eng. Regen. Med., 7(8):665-672. (Impact Factor:4.428, Ranking: 5/76, subject categories: Engineering, Biomedical, published: August, 2013).

8. Yu-Ko Liu, Chih-An Yang, Wen-Ming Chen and Yu-Hong Wei* (2012) Producing bioethanol from cellulosic hydrolysate via co-immobilized cultivation strategy., J. Biosci. Bioeng., 114(2), 198-203, SCI. (Impact Factor: 1.869, Ranking: 42/123, subject categories: Food Science & Technology).

9. Bor-Yann Chen, Tz-Jau Shiau, Yu-Hong Wei*, Wen-Ming Chen, Bing-Hua Yu, Chia-Yi Yen and Chung-Chuan Hsueh (2012) Feasibility study of polyhydroxy- alkanote production for materials recycling using naturally occurring pollutant degraders., J. Taiwan Inst. Chem. Eng., 43, 455-458, SCI. (Impact Factor: 2.637, Ranking: 23/133, subject categories: Engineering, Chemical, published: May, 2012).

10.Chien-Hsing Lu, Shin-Chang Lin, Shu-Yi Yang, Mu-Yun Pan, Yun-Wei Lin, Chun-Yi Hsu, Yu-Hong Wei, Jo-Shu Chang, Chia-Che Chang* (2012) Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines. Toxicol. Lett., 83-89, SCI (IF: 3.355, Ranking: 20/87, subject categories: Toxicology, published: June, 2012).

11.Chih-Ching Chien, Hsiu-Hsiung Li, Po-Chi Soo, Shan-Yu Chen, Yu-Hong Wei* and Wen-Ming Chen (2012) Effects of different substrate composition on biosynthesis of polyhydroxybutyrate-co-hydroxyvalerate by recombinant Escherichia coli. Appl. Biochem. Biotechnol., 166, 796-804, SCI. (Impact Factor: 1.687, Ranking: 102/165, subject categories: Biotechnology & Applied Microbiology, published: January, 2012).

12.Bor-Yann Chen, Tz-Jau Shiau, Yu-Hong Wei*, Wen-Ming Chen, Bing-Hua Yu, Chia-Yi Yen and Chung-Chuan Hsueh (2012) Feasibility study of polyhydroxy- alkanote production for materials recycling using naturally occurring pollutant degraders., J. Taiwan Inst. Chem. Eng., 43(3), SCI. (Impact Factor: 2.637, Ranking: 23/133, subject categories: Engineering, Chemical, published: May, 2012).

13.Bor-Yann Chen*, Tz-Jau Shiau, Yu-Hong Wei, Wen-Ming Chen (2012) Feasibility study on polyhydroxybutyrate production of dye-decolorizing bacteria using dye and amine-bearing cultures., J. Taiwan Inst. Chem. Eng., 43(2), SCI. (Impact Factor: 2.637, Ranking: 23/133, subject categories: Engineering, Chemical, published: March, 2012).

14.Yu-Hong Wei*, Wei-Chuan Chen, Ho-Shing Wu and Om-Murugan Janarthanan (2011) Biodegradable and biocompatible biomaterial, polyhydroxybutyrate, produced by an indigenous Vibrio sp. BM-1 isolated from marine environment., Mar. Drugs, 9(4), 615-624, SCI. (Impact Factor: 3.512, Ranking: 10/58, subject categories: Chemistry, Medicinal; published: April, 2011).

15.Yu-Hong Wei*, Fang-Wei Yuan, Wei-Chuan Chen and Shan-Yu Chen (2011) Production and characterization of ectoine by Marinococcus sp. ECT1 isolated from a high-salinity environment. J. Biosci. Bioeng., 111(3), 336-342, SCI. (Impact Factor: 1.869, Ranking: 42/123, subject categories: Food Science & Technology, published: March, 2011).

16.Yu-Hong Wei*, Wei-Chuan Chen, Chin-Kuei Huang, Ho-Shing Wu, Yi-Ming Sun, Chi-Wei Lo and Om-Murugan Janarthanan (2011) Screening and evaluation of polyhydroxybutyrate- producing strains from indigenous isolate Cupriavidus taiwanensis strains., Int. J. Mol. Sci., 12(1), 252-265, SCI. (Impact Factor: 2.339 Ranking: 52/148, subject categories: Chemistry, Multidisciplinary; published: January, 2011).

17.Wei-Chuan Chen, Chao-Ling Yao, I-Ming Chu, and Yu-Hong Wei* (2011) Compare the effects of chondrogenesis by culture of human mesenchymal stem cells with various type of the chondroitin sulfate C. J. Biosci. Bioeng., 111(2), 226-231, SCI. (Impact Factor: 1.869, Ranking: 42/123, subject categories: Food Science & Technology, published: February, 2011).

18.Chia-Che Chang, Wei-Chuan Chen, Tsing-Fen Ho, Ho-Shing Wu and Yu-Hong Wei* (2011) Development of natural anti-tumor drugs by microorganism. J. Biosci. Bioeng., 111(5), 501-511, SCI. (Impact Factor: 1.869, Ranking: 42/123, subject categories: Food Science & Technology, published: May, 2011).

19.Wei-Chuan Chen, Chao-Ling Yao, Yu-Hong Wei* and I-Ming Chu (2011) Evaluating osteochondral defect repair potential of autologous rabbit bone marrow cells on type II collagen scaffold. Cytotechnology., 63(1), 13-23, SCI. (Impact Factor: 1.315, Ranking: 113/160, subject categories: Biotechnology & Applied Microbiology, published: January, 2011).

20.Yu-Tze Horng, Chih-Ching Chien, Yu-Hong Wei, Shan-Yu Chen, John Chi-Wei Lan, Yi-Ming Sun and Po-Chi Soo* (2011) Functional cis-expression of phaCAB genes for poly(3-hydroxybutyrate) production by Escherichia coli. Lett. Appl. Microbiol., 52(5), 475-483, SCI (Impact Factor: 1.629, Ranking: 103/160, subject categories: Biotechnology & Applied Microbiology; published: May, 2011).

21.Wei-Chuan Chen, , Yu-Hong Wei, Jui-Bin Huang, I-Ming Chu and Chao-Ling Yao* (2011) Biological effects of oligosaccharide chondroitin sulfate C on human articular chondrocytes. Biomed. Eng.-Appl. Basis Commun., 23(3), 245-252, SCI (Impact Factor: 0.233, Ranking: 75/79, subject categories: ENGINEERING, BIOMEDICAL; published: June, 2011).

22.Chi-Wei Lo, Ho-Shing Wu* and Yu-Hong Wei (2011) High throughput study of separation of poly(3-hydroxybutyrate) from recombinant Escherichia coli XL1 blue., J. Taiwan. Inst. Chem. Eng., 42(2), 240-246, SCI (Impact Factor: 2.637, Ranking: 23/133, subject categories: Engineering, Chemical, published: March, 2011).

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